Monday, 9 January 2017

What are the different kinds of laboratory tests and methods to avoid contamination f the removed tissues from women body??

Then, what may be ideal economically affordable solutions of the problem: - i.e. difficulties in diagnosis of Genital Kochs??

 I am personally more in favour of Lap & hysteroscopy if serious doubt exists in a given case.
Because, by doing Lap & hysteroscopy one can collect many portions of samples from many sites(hopefully now without any environmental  contamination-as happens in Mens Blood collection) and I prefer to order following testsà All reports collectively, hopefully can exclude / confirm the diagnosis of TB :-After removing tissues from womb or tummy one can put such excised tissues for following investigations:
Such tests for TB are 1) Conventional   Histological diagnosis –Cornual region biopsy -can be performed with fair degree of accuracy-Z-N stain, & Normal saline stain AFB smear,, 2) Rapid culture-Bactec-460 in Co incubator, 3)  Delayed culture-in L-J media –such growth of bacteria in a special media will be of considerable help  to confirm  initial diagnosis’ based on H/O contact with Koch’s (particularly in close family members,) and 4) blood count :-raised TC & Lymphocytosis  (raised -level of one type of blood cells).

Firstly, No ATD based on Menstrual  blood report only:-Such blood test was very popular and still practiced all over world as because e as it is a noninvasive tests.. But I don’t consider that ATD should ever be prescribed based on Menstrual  Blood report. If there is +ve family history of Koch’s or say  H/O contact and irregular fever, loss of wt then one can at best  advise Chest X-ray & diag Endo biopsy / Hysteroscopy & endometrial assessment for Koch’s 1)  by Conventional,(should I call traditional)  AFB satin -Z-N Stain) ,. Culture for Koch’s bacilli includes 2) Bactec Test; 3) Rapid &4) Delayed cultures à followed by drug sensitivity tests which is often omitted by us. , 

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