A) Simple ovulation induction:
By clomiphene / letrozole or rearly TMX (Tamoxifene- an anticancer drugs for barest
cancer at low dose of 20 mg or 40 mg on dely basis for 5 days per cycle. But
the fact remains one has to monitor the cycle by TVS on day nine, then
according to the size of the follicle another at least 2 or 3 such TVS is mandatory.
Because it is no point giving any of the three drugs maintained above for month
toughte4r remaining blind about the efficacy of the drugs in inducing ovulation.
AT LEAST THE FIRST or second cycle should be monitored so that we can switch
over to some other agent without wasting valuable months and adding frustration
of the couple.
B) Controlled ovarian stimulation: & Superovulation:
Ans: What is meant by Simple ovulation? In this type of Simple ovulation induction no IUI or ART (IVF) are attempted. The
idea, as opposed to ART is to induce mono-follicular development in
anovulatory /oligo-ovulatory subfertile women. This procedure is relatively
simple and poses little effort on the part of doctor and acceptable for
subfertile coupe as it warrant minimum visits to clinics. Further, it is a
purely noninvasive in nature as OPPOSED TO IUI OR ivf .However the agent most
commonly employed to induce ovulation is clomiphene citrate. Occasionally 1)
anstatrozole (letrozole) group of drugs are used and 2)
more rarely Tamoxifen is used mainly in cases where there is persistent thin
endo in CC cycle as an alternative to hMG cycle (Cost saving approach)...
C) Superovulation: which is a common protocol in IUI
procedures? Different from stimulation
of multiple follicle development in ovulatory women, as is done with assisted
reproductive techniques.
How the Ovulatory disorders / deficiencies as are defined so as to
select the optimum drugs or measures to achieve ovulation at a minimum time...
The classification as suggested by the WHO is:
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