Hyperthyroidism
: Women thyroid stimulating
antibody activity declines during pregnancy associated
with chemical remission. When
mild thyrotoxicosis may be difficult to diagnose during pregnancy overt can be easily diagnosed. The diagnosis
is confirmed when an
abnormally low thyroid stimulating hormone level is accompanied by
abnormally high serum triiodothyronine levels - . The
major cause of
hyperthyroidism in pregnancy is Graves disease an organ specific autoimmune process usually associated with thyroid
stimulating antibodies. In
many women thyroid
stimulating antibody activity
declines during pregnancy
associated with chemical remission.
Pregnancy outcomes depend upon
whether metabolic control is achieved .women
who remain hyperthyroid despite
therapy and in those whose disease
is untreated there is a higher incidence
of preeclampsia heart
failure and adverse perinatal outcomes. Thyroid storm is encountered
only rarely in untreated women
with Graves disease. Heart
failure is more common than T storm cases.
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