Wednesday, 28 September 2016

Safest Contraceptive Pill-Minikare Tab to be taken daily. Very safe contraceptive .

 What is Minikare Contraceptive Tablet ?? Why  modern women should not use safest Contraceptive pills i.e. Old generation Progesterone only Pills -Which can be safely  used in medically sick women . e.g. those who hypertensive / diabetic women . In our country such safe PO are available .Indian women may use "MINIKARE " contraceptive pills : PCK OF 28 TABLETS-COST about Rs..210/- PER PACK.
OLD generation POP (Traditional POP):
            History of POP dates back from 1965. As many as five different Progesterones (female sex hormones) have been used earlier, before modern POP. (POP containing Desogestrel hormone) gained globally popularity. The previous Progesterones tried (as POP progesterone only pill) are rarely used nowadays because are less effective than modern POP. Only on special situations one can use them. The following paragraph details the characteristics of Old POPs.

Salient Features of Old POP:
            These products are still continued to be used abroad but these are not available in Indian market.

Classification of POP: There are three broad types of POP:
            Earlier, first generation progesterone (chlomadinose) was used as POP. This type of POP is no more used in any country. Later norgestrel (Microlut, ovrite) and norethidrone (Micronor) were used. These Progesterones were termed as second generation POP. These second generation of POP as cheap and still used in elderly women in some countries but sadly these cheaper second generation minipill have never been available in India. The third generation progesterone hormone (is however Desogestrel containing) POP.  Minikare is the name of Indian Brand of such contraceptive.Which is the only POP available in India? 
           

Advantages of Old POP:
1)      Cheaper than newer POP. 2) More effective in prevention is STD as the primarily mode of action as contraceptive is ‘increased thickness (i.e. viscosity) of cervical mucus’. If the secretion of the cervix (mouth of womb) is thick then neither sperm nor STI organism can enter into womb (uterus). 3) Does not depress ovarian function. Unlike Desogestrel (new POP). Old POPs don’t suppress ovulation in 40-50% occasions. But by making more aggressive changes in cervical mucus these drug prevent conception quite effectively. (Modern POP, available in Indian market, exerts much less action on cervical mucus than old POP. Thus has little action on prevents STI). 4) Minimal excretion in breast milk: In comparison to modern POP, old POP is minimally excreted n breast milk. So some scientists consider that possibly old POP is safer than new POP (Desogestrel) for lactating mothers. But opinion amongst scientists still differs and more research is needed on this issue. But all scientist umamimonusly agree both traditional POP and new POP are equally safe for body, no matter how much quality is excreted in breast milk. Thus to a couple the choice of POP (Old or New) is a question of Price. 5) For walking lady this type of POP may be a better option as bleeding related side effects are less with old type POP. But frequency amenorrhoea (prolonged cessation of menstruation) is more common than POP.

Disadvantage of Old type POP:
1)      Added precaution will be needed if someone is late to take the pill beyond three hours. By contrast this safety margin is twelve hours in case of modern POP if not more as it often supposes ovulation.
2)      Androgen like side effects like acne, aloplecia is more common because these old type of POP exerts effects like male hormone (androgen).
3)      Contraceptive failure rate is high. Modern POP effectively suppresses ovulation in 97% treatment periods. Therefore new POP offers greater contraceptive reliability than traditional POPs. The failure rate of old POP is 0.3 to 4 per 100 women year which is a bit high than modern POP (0.2-0.9). Thus Old POP even if taken regularly, the failure rate (method failure is slightly higher than present day POP. But to average women this is insignificant particularly in women who enjoy some degree of natural protection e.g. lactating women and women beyond 42 years. Occurrence of regular  ovulation in these women is uncommon.

No comments:

Post a Comment