How many of us are aware thet degree of hyperandrogenism
change with advancingage age incases of
PCOS??
We know
that elevated serum concentrations of androgens are the most consistent
biochemical abnormality and is often considered as the hallmark of the PCOS syndrome .This
conclusion is arrived after the fact that there is an age-related decrease in
androgen secretion, as in normal women, such also occurs in women with PCOS. Many studies have
observed that hyperandrogenic women exhibit a negative association between
DHEAS levels and age. It has also been observed time and again that all the three common serum androgen markers namely, total testosterone,
androstenedione, and DHEAS were
significantly negatively correlated with age. Additionally, it have been also
observed that the incidence of acne and hirsutism decreased with advanced
age, as is mF-G score, and serum DHEAS
levels.
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