Indications of Vaginal micronized A) soft gel Capsule 100/ 200 mg or B) Vaginal
Gel form as 90 mg of progesterone.
Following are the “Guidelines
published by RCOG,ACOG,EAFM,SOGC “-- all
such academic bodies unanimously
recommended that micronized progesterone or vaginal gel as progesterone have a definite
role in prevention PTL or retardation of
Preterm labour(PTL/PTM); The recommendations of such distinguished academic
bodies are as follows :
A) 100 mg Micro Progesteerone soft
gel --When to prescribe 100 mg Micronized Progesterone soft gel and not 200mg
unnecessarily ? Indications are:-In
women who had history of previous PTL. Such type prophylactic progesterone,
based on history alone has been termed as “Early prophylaxis use of Progesterone”-which
is imitated from 12 weeks –to 36 weeks of gestation. The decision of 10 mg vaginal
soft gel or 17-OH progesterone from 12 weeks to 36 weeks (source:-Di Renzo GC
et al: --The European Association of Perinatal Medicine Study Group on Preterm
Birth-- Guideline for the management of spontaneous preterm birth
.diagnosis, identification of spont PTB, diagnosis of
spont preterm rupture of membranes and preventive tools for PTB: J Maternal
Foetal Neonatal Med 2011; 24: 659-67.All
such academic bodies have agreed irrespective of sonological evidence of Cx dilatation or short
Cx.
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