)
200 mg micro when ?? When to prescribe
200 mg Micronized Progesterone soft gel/ or Crinone gel ( 90 mg) at morning ? In cases of singleton pregnancy, with or without
past history of PTBà
but there is recent sonological evidence of a) short cervical length < 25
mm at 18-23 weeks. The said study group
have observed that is used vaginally (not oral) and not 100mg vaginal
micronized progesterone. FIGO too have strongly recommended this preventive
steps and FIGO Group suggested no oral Tab but either 200mg Micronized
Progesterone (at nighttime) / Crinone or
Susten gel , 90 mg
( Cost per gel ₹112
-)/
2.Naturogest 8%
Vaginal gel(Zydus Cadila
₹93.26/gm of Vaginal gel
All such gel
formulations should be applied at
morning- for reason not clear to me .
Anyone can push the soft gel at night time but as hands becomes unclean for the
whole night I, Dr Pal feel, in this
context that husband if present at
home may push the tab at nighttime so
that she need not stand up soon after
the micro 200mg is inserted at bed time by herself, Counsel: that not to use tampons or
other vaginal products for at least 6 hours before and 6 hours after using
Crinone 8% Vaginal gel. So to summarize all
short Cx of 25 mm at 18-23 weeks of gestation. No oral , No Inj 17 OH
progesterone ( Source:-Extract from a
Book: titled” Progesterones in Obstetrics & Gynaecology”: Sponger
Publications: Ed Howard JA,carp :: ISBN 978-81-322-4499-8: Ed 2015 p.89
What are the trade names of Vaginal Progesterone gel &
cost as on date available in India:-1.Susten 8% Gel(Sun
Pharmaceutical Industries Ltd) ₹112/Vaginal gel::
2.Naturogest 8%
Vaginal gel(Zydus Cadila₹93.26/gm of Vaginal gel
3. Gestone 8% Vaginal gel(Ferring Pharmaceuticals:₹7.35/gm of
Vaginal gel)%
4)Urea Vaginal gel(Intas Pharmaceuticals Ltd) ₹126.92/gm of
Vaginal gel
5) Emprogest 8%
Vaginal gel (Emcure Pharmaceuticals Ltd₹199.25/gm of Vaginal gel)
What are the other uses of 200 mg of micronized Progesterone;-In
women who had one episode of Thr. Preterm labour in current pregnancy?
400 mg when?? Four
hundred Progesterone is used in cases of
Acute tocolysis that
too for 48 hrs only later after cessation of contractions one should taper the
dose to 200mg Prog vaginally daily till
36weeks., Therefore in established PTL
where we intend to use acute tocolysis then vaginal
micronized 400 mg daily in divided doses
in conjunction with other parenteral or tocolytics (like Nifedipine, Ritodrine, )
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