Sunday, 16 October 2016

Are your subfertility problem is due to poor movement of sperms-called astheno-zoospermia (poor or no movement of male egg cells)? Is your male partner suffering from absence of sperms in semen? Think of genetic disorders if no obvious cause is attributed by routine evaluation.

In cases of no sperms in semen (azoospermia) or very poor or absence of movements of sperms in the liquefied semen (severe asthenospermia) - mandate a detailed evaluation by andrologist and thereafter by a clinical geneticist. Need not be morosed . Some recent methods (like artificial reproductive technology-commonly called ART procedures)  will be available to U .May consult an andrologist or clinical Geneticist for genetic studies. Majority of idiopathic male infertility (30-40%) are associated with genetic abnormalities. Few also are due to structural abnormalities of chromosomes where all genes are packed up which can easily picked up by a test called Karyotyping. But diagnosing genetic disorders is a difficult task altogether and require special  skill and Laboratory.


When to consider that it is time to consult a geneticist?  It is not impossible to imagine & accept tubal ciliary disease (like men suffering from-Immotile Cilia Syndrome, or full fledged Kartagener’s syndrome (KS) with about health of tubal cilia and resultant subfertility. When we think of the possibility  of Kartagener’s syndrome (KS)   /primary ciliary dyskinesis/ Young Syndrome/ Cystic Fibrosis  disease/ CBAVD Should we then carefully auscultatate heart & Lungs,  and search for other somatic components which are likely to be present in males with KS  (as we do in all cases of motility disorder in men) in women with unexplained subfertility.



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