The relevance of Peripheral smear of a
thin blood slide?? How many of us
scrutinize the report page of peripheral blood
smear as soon as blood Hb is <
10 Gm at antenatal OPD ?? .Ans: Seldom we do so.
But many cases the etiology of anemia
can be identified by carefully observing
the P blood smear report and thereby may
avoid detailed investigations in many cases. This is so relevant in our
developing country but many diagnois are
written if we read in between lines though complete haemogram have partially replaced many daig
features of P smear. . .many are in between the line of that report. How many
of us seriously enquire about added F acid , Vit B 12 suppl before coming to any
Medl college with Hb of 6 Gm at 34 weeks???
How many of us seriously examine
lymphadenopathy, sternal tenderness, hepatosplenomegaly, see tongue, nail pattern and ask for oesophagitis for Plummer Vinson syndrome, insist on Stool
for occult blood exam . Or say else enquire about the cooking habits of the
family , Toilet facility at fields, (hook worm)
& dietary pattern , habit tea & Coffee in particular (Iron absorption
inhibitors)!! Seldom we enquire about Vegans/ Nonveg ?? Hope from
tomorrow we will do for Indian women,
Causes of anemia::
Physiological - Pregnancy causes
a state of hydraemic plethora. There is disproportionate increase of plasma
volume during pregnancy leading to apparent reduction of RBC, haemoglobin and hematocrit
value. Hb is consequently reduced to a varying extent occasionally as low as
80%. The dilution picture is normochromic and normocytic. This is so called
physiological anaemia.
Iron deficiency anaemia (60%),
Acquired- Nutritional (Microcytosis with hypopigemented central area in P smear
)
Macrocytic anaemia (10%) due to
deficiency of folic acid and/or vitaminB12 Acquired- Nutritionalà
again P smear will speak .Dimorphic and protein deficiency anaemia (30%) both
due to deficiency of iron and folic acid and /or vitaminB12
Protein deficiency -due to
protein deficiency in extreme malnutrition.
Hemolytic or Haemorrhagic (due to
acute blood loss,; chronic (hook worm, bleeding piles). Different kinds of
cells Poikilocytoisis /Ovale cells, Tear drop cells will speak & raise a
suspicion
Risk factors 1) Sociodemographic
factors (age, level of formal education, marital status, areas and cities of
residence).Obstetrical factors (gravidity, parity, history of previous preterm
or Small-for- gestational-age deliveries, plurality of pregnancy—multiple Or
singleton)
Behavioral factors (smoking or
tobacco usage, alcohol usage, utilization of prenatal care services)
Medical conditions (diabetes,
renal or cardio-respiratory diseases, chronic hypertension AIP—anemia in
pregnancy
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