Endometriosis :: Failure of adequate luteolysis is a second aspect of luteal dysfunction in endometriosis and strongly supports the growing body of data confirming ovulatory asynchrony in the minimal; endometriosis infertility syndrome.has been associated with corpus luteum
inadequacy and abnormalities of luteal phase progesterone (P) secretion. In
this =disease abnormal luteolysis, as a second factor of luteal dysfunction, was
assessed with endometriosis =Measurement
of ovarian vein estradiol (E2) and P during the follicular phase. The results
reveal that women with endometriosis have (1) significantly lower ovarian vein
E2, significantly higher both peripheral and ovarian vein P, and (3)
threefold higher P/E2 ratios than controls during the follicular phase. These support the concept of continued P production from an active corpus luteum
well into the follicular phase of the following cycle in women with
endometriosis. Failure of adequate luteolysis is a second aspect of luteal
dysfunction in endometriosis and strongly supports the growing body of data
confirming ovulatory asynchrony in the minimal; endometriosis infertility
syndrome.
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