Polyzoospermia

Polyzoospermia: Can this entity, albeit rare may be a cause of male factor subfertility ?? Prevalence of Polyzoospermia in fertile and subfertile men in India?? Let us very briefly recapitulate  what is supposed to occur in the sperm production factory. What’s wrong going on there in  cases of polyzoospermia ??

We know that a primary spermatocyte is transformed into two secondary spermatocytes during meiosis I - &  these cells then in turn are converted into (1N) spermatids during meiosis II To my knowledge, the errors of cell division  occur  here in cases of polyzoospermia. In such cases which may yield  polyzoospermia   one primary spermatocyte divides (meiotic) not into  2 cells but erratically to 3 or 4 sperms.( ?  abnormal mood of gene controlled/ Growth factor related).  As too many daughter cells coming from each pri spermatocytes as such each sec sperm possesses  less amount of DNA/Mitochondria. This suboptimal DNA content in cases of polyzoospermia is the possible explanation of male factor subfertility or say early preg loss (failure to progress normally after fertilization-Early embryonic demise) . As primary spermatocytes has fixed amount of DNA which is meant for ideally for 2 Sec spermatocytes has now divided in 3 cells with so less DNA per daughter cells.

What about women??As a corollary in women too , such erratic cell division may rarely which is expressed as  polyovular follicle when one D F exhibits two oocytes with a single Liq Folliculi and two Cumulus !!!

In males such erratic division of parent cells is expressly as Polyzoospermia and in women such erratic cell division of parent cells may be exhibited by  Polyovular follicle which may —May be  a cause of MAMC twin!! Members pl opine. I am very old man with poor memory at 76 yrs.