How
many members use stains in teenage PCO if there is marked dyslipidaemia??
Ans:
This raises a question is it worthy to prescribe such drug when hepatic
enlargement is not uncommon (Fatty liver). How should one balance the risk of stating
induced myopatly albeit rare.Does stain have
any long term beneficial effect Ion risk reduction in the form of CVD prevalence
.Does stain prevent prevalence or magnitude of CVD in later life?What does the
evidence say??
What
is known about PCO;-We are aware of the fact
that high levels of serum androgens
(male hormone) are one of the main features of PCOS.
women
with polycystic ovary syndrome (PCOS) usually suffer from irregular periods, excessive hair growth
(hirsutism) and acne (pimples).
How many members use statins in PCO when there is
dyslipidaemia at post pubertal age due to PCO to curtail CVS risk in later life?
We know post-pubertal girls who are having Oligomenorrhoea, overweight along with F/H/O
of DM are at a higher risk of Metabolic syndrome & CVD in of 4th/5th
th decade of life . But the magnitude of
risk(how early will the and how severely the woman will be affected but the
fact remains that OGTT is a better guide for glycemic status of adolescent PCO
abd Lipid profile to forewarn the parents about diet & exercise).
Ans 2:-There is no good evidence from different long term studies that ` :-
Statins improve menstrual regularity, spontaneous ovulation
rate, hirsutism or acne, either alone or in combination with the combined oral
contraceptive pill.
There is also no good
evidence that statins have a beneficial effect on hirsutism or acne (pimples)
associated with PCOS.
But the plus point is :-- In women with PCOS, statins are
effective in reducing serum androgen levels and decreasing bad cholesterol
(LDL), but
statins are not effective in reducing fasting insulin or
insulin resistance. There is no good evidence available on the long-term use of
statins (alone or in combination) for the management of
PCOS.
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