Polycystic
ovaries are a separate entity and have a distinct response to induction of ovulation and ovarian stimulation for IVF. The
association of enlarged, sclerocystic ovaries
with amenorrhoea, infertility and hirsutism was first described by Stein and Leventhal in 1935, and it is now known as PCOS.
Since then, it has become apparent that polycystic ovaries may be present in
women who are non-hirsute and who
have regular menstrual cycles. Thus, a clinical spectrum exists between the typical
Stein—Leventhal picture (PCOS) and the symptomless (PCO). Even patients described as having the PCOS exhibit considerable
heterogeneity.
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