The polycystic ovary should have at least one of the following:
either 12 or more follicles measuring 2-9
mm in diameter or increased ovarian volume (>10 cm3). If
there is evidence of a dominant follicle (>10 mm) or a corpus luteum, the scan should be repeated the next
cycle.
The subjective
appearance of polycystic ovaries should not be substituted for this definition. The follicle distribution should be omitted
as well as the increase in stromal
echogenicity and/or volume. Although the latter is specific to PCO, it has been shown that the
measurement of the ovarian volume is a good surrogate for the
quantification of the stroma clinical practice.
Only one ovary
fitting this definition or a single occurrence of one of the above-mentioned criteria is sufficient to define the PCO. If
there is evidence of a dominant follicle (>10 mm) or corpus luteum, the scan
should be repeated the next cycle. The
presence of abnormal cysts or ovarian asymmetry, perhaps suggesting a
homogeneous cyst, necessitates further investigation.
This definition
does not apply to women taking the oral contraceptive pill, as ovarian size is reduced, even though the
polycystic appearance may persist.
A woman having PCO in the absence of an
ovulation disorder or hyperandrogenism
(asymptomatic PCO) should not be considered as having PCOS, until more is known about
this situation.
In addition to its
role in the definition of PCO, ultrasound is helpful to predict fertility
outcome in patients with PCOS (response to clomifene citrate, risk for ovarian hyperstimulation syndrome
(OHSS), decision for in vitro maturation
of oocytes). It is recognised that the appearance of PCOs may be seen in women undergoing ovarian
stimulation for IVF in the absence of overt signs of the PCO syndrome. Ultrasound also provides the
opportunity to screen for endometrial hyperplasia following technical recommendations
should be respected.
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