Sunday, 24 March 2019

Diagnosing Koch’s with great caution!!What caution in the diagnostic path? What is the caveat in Koch’s??


Genital Koch’s:- Take home message:
When to suspect tuberculosis of the pelvis leading to tubal blocks causing infertility. For diag we the clinicians have to rely on many things, For instance 1) history, 2) pelvic examination like any pelvic adhesion, immobility of uterus, fixity 3) findings in   ultrasound, 4) HSG, 5) laparoscopy, 6) culture, 7) histopathology .If any one or two criteria offers a suspicion i.e. whichever could make us suspect tuberculosis of the pelvis leading to tubal blocks causing infertility.

Diagnosing Koch’s with great caution!!What caution in the diagnostic path? What is the caveat in Koch’s?? The sheer presence of the bacilli in the body (without damaging the tubes), at least in subfertility cases does not stop the women from becoming pregnant. All over the world including the western part of the world where tuberculosis is unheard off, tubal blocks are responsible for 25% to 30% female infertility (poly-microbial infections, Chlamydia and miscellaneous pelvic infections are responsible for the tubal disease). India being a developing overpopulated country will logically also have the same share a 
There is no comparison between the use of ATT and empirical use of doxycycline (as quoted to be used by some clinicians in the west) for infections like Chlamydia. The duration of treatment, toxicity, morbid complications, difficulty in ingestion and the risk of emergence of drug resistance of ATT compared to aforementioned drug is world apart.
 Indiscriminate use of anti-tubercular treatment??  Indiscriminate use of anti-tubercular treatment based on a flimsy and flawed premise such as positive TB PCR or other indirect screening test for latent tuberculosis (incidence of latent TB is more than 40%) leads to a very real and present danger of the emergence of multi-drug resistant strain, which remains the biggest challenge for NRTCP health personnel’s battling active tuberculosis in India today.

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