No ovulation as a result no pregnancy:-What is WHO Class II anovulation?? Anovulatory Infertility: Not all causes of an ovulation can be ascertained even in the best lab of world:-Anovulatory Infertility: Of many causes of anovulatory subfertility, in most cases a cause can be ascertained and reproducible by Lab tests., But a fair no of cases of anovulatory the cause of anovulation remains  uncertain and . but others can’t be documented, In such cases  where no cause  can be ascertained we quite often empirically prescribe ovulation inducting agents likes or Letrozole with the expectations these may be induce ovulation irrespective of the cause, But today my topic is the issue of Hyperprolactinaemia may be a cause of Anovulation(WHO Class III)  Ovulation Induction.WHO III anovulation:-Diag & management Causes of Hyperprolactinaemia: Pharmacological Hyperprolactinaemia:--The commonest cause is now a days is:-several drugs (e.g. the dopaminergic antagonists phenol-
Thiazines, selective serotonin reuptake inhibitors (SSRIs), domperidone and metoclopramide). In fact, the SSRIs are now the most common cause of drug-induced Hyperprolactinaemia 
Tips 1:--Not to prescribe Bromocriptine or say Cabergolin if a) PRL is < 50 b) No LPD c) no an ovulation d) no early preg loss and e) no demonstrable Galactorrhoea in absence of pharmacological Hyperprolactinaemia, Ladies and gentleman Hyperprolactinaemia may cause 1) LPD 2) poor Ovum quality too poor to get fertilize or failure to grow after fertilization &cleavage. Failure to fertilize or early preg loss 3) Anembryonic preg or Blighted ovum 6) anovulation; 
Tips 2:-: If the prolactin concentration is slightly raised and she is having regular cycle then no need to prescribe Bromocriptine or cabergolin so long as ovulation is there or there no Lab evidence of LPD (low P value in serum on day 23 of regular cycle) of regular menstruation, there is no evidence that treatment is warranted so long as value is below< 50 IU of PRL,