Emperical uzse of nerves & amelioration of nereve pains

Good morning. Have you time to know about GABA derivatives( Pregabalin) & Gabapentin( GABA analogue):-GABA has been promoted as Neuroprotector. There are two main drugs that are used albeit empirically in neuropathic pain & mood changes in midlife of women (as anxiolytic). These two drugs are termed as namely A) Pregabalin & Gabapentin.

Former agent (Pregabalin) a GABA derivative is of little  used in our discipline. This drug is used mostly used in epilepsy & post stroke,. Initially at the dose of 50 mg OD, later 50 mg TDS. Maximum 300 mg OD.,. Brand names are Pregabid(Intas) Pregalin( Torrent) & Gabaneuron(Aristo).I have no experience of using this drug.

The second drug: GABA analogue:-But I have used second  drug i.e. Gabapentin ,This is an GABA analogue. Though like Pregabalin, this drug is also used for epilepsy but it is also used in our discipline for four  indications albeit not on regular basis or as primary drug. Such four  indications of GABAPENTIN are 1) Anxiolytic, 2) use 1:-Diabetic neuropathy ( DOSE 900-1299 mg od), Peripheral & central neuropathic pain, including pain at abd scar site when the lateral incision is cut too lateral –cut br of lateral femoral nerve is cut , use 2:- Pudendal neuropathy, use 3:- thirdly in Restless Leg syndrome-300 mg OD ,  as you watch at your chamber(such Pts are always moving their legs-like dancing their knees ?? This abnormal movement may be an expression of OCD-Obsessive Compulsive Disorders).. Use 4: Anxiolytic –may also sometimes used in Endometriosis: - Use 5 Another use  is Post-herpetic neuralgic pain when this drug Gabapentin is prescribed freely  at the dose of 300 mg TDS. The trade names of Gabapentin are Gabapin(INTAS): Gabatin, Gabapentin(ABBOTT), Gabantin(Sun Synergy)