SMALL OVARIES:
Ovaries get smaller from puberty to menopause because
they lose their follicles and eggs.
Thus, they are less capable of:
• Normal growth (folliculogenesis) and hormone production
• Egg maturation and ovulation
Thus, they are less capable of:
• Normal growth (folliculogenesis) and hormone production
• Egg maturation and ovulation
Ovarian Measurements and Fertility
Based on data from the Human Reproduction Update (HRU)
article, the average length of each ovary is:
• During the reproductive years (age 15 to 44): Three to five centimeters
• During the perimenopause (age 45 to 50): One and a half to two and a half centimeters.
• During the reproductive years (age 15 to 44): Three to five centimeters
• During the perimenopause (age 45 to 50): One and a half to two and a half centimeters.
Ovarian Volume
• In the reproductive years: 18.3 cm³
• At menopause: 8 cm³
• Post menopause: 2.2 cm³ (15 years after).
• In the reproductive years: 18.3 cm³
• At menopause: 8 cm³
• Post menopause: 2.2 cm³ (15 years after).
IVF OBSERVATIONS:
• Poor response of the follicles to fertility drugs -
failure to grow and increase estrogen output
• More than a 50% risk of canceled IVF cycles before egg retrieval due to poor follicle and egg development.
• More than a 50% risk of canceled IVF cycles before egg retrieval due to poor follicle and egg development.
Ovarian Aging and
Fertility Rates
In a study published in 2010 in the journal PLOS One, the Edinburgh University scientists the average percentage of follicles remaining in the ovaries is as follows:
• Age 30: 12%
• Age 37: 5%
• Age 40: 3%
• At menopause (age 50-51): Less than 1% - only about 1,000 follicles remain, corresponding to a volume of 3 cm³ for each ovary
In a study published in 2010 in the journal PLOS One, the Edinburgh University scientists the average percentage of follicles remaining in the ovaries is as follows:
• Age 30: 12%
• Age 37: 5%
• Age 40: 3%
• At menopause (age 50-51): Less than 1% - only about 1,000 follicles remain, corresponding to a volume of 3 cm³ for each ovary
Decrease in Fertility Rates With Age
According to a 2013 Human Reproduction Update review on ovarian aging, because of the loss of follicles and volume of the ovaries with age, compared to women age 20-24, fertility rates decrease as follows:
• Age 25-29: 6%
• Age 30-34: 14%
• Age 35 -39: 31%
According to a 2013 Human Reproduction Update review on ovarian aging, because of the loss of follicles and volume of the ovaries with age, compared to women age 20-24, fertility rates decrease as follows:
• Age 25-29: 6%
• Age 30-34: 14%
• Age 35 -39: 31%
Other Causes of Small Ovaries
• Premature ovarian insufficiency causing early loss of In addition to the natural loss of follicles and the decrease follicles
• Infection or inflammation of the ovaries
• Removal of part of the ovary during previous surgery
• Chemotherapy or radiation
• Premature ovarian insufficiency causing early loss of In addition to the natural loss of follicles and the decrease follicles
• Infection or inflammation of the ovaries
• Removal of part of the ovary during previous surgery
• Chemotherapy or radiation
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