Saturday, 5 October 2019

How helpful is Uterine artery Doppler at 23 weeks in predicting FGR or PIH or both??


FGR  AND ROLE OF USG :-How relevant is Doppler examination of the uterine arteries ? Out of 100 cases screened for Ut A Doppler it is estimated that   about 10% cases   had early diastolic notches in the waveform from both uterine arteries, Additionally in additional 11.1% cases there   were notches unilaterally. Pre-eclampsia with fetal growth restriction occurred in 0.5%  cases, pre-eclampsia without fetal growth restriction in 0.9%  and fetal growth restriction without pre-eclampsia in  .9%. The (sensitivity of increased pulsatility index above the 95th centile,
Q. 2: What about umbilical artery?? At a mean gestational age at  23 weeks Umb artery PI (pulsatility index)--did not change significantly with gestation  the median value of PI  was 1.04 and the 95th centile was 1.63 If PI is 1.63 then we can conclude :--A)   for pre-eclampsia with fetal growth restriction was 69%, B)  for pre-eclampsia without fetal growth restriction was 24%, C)  for fetal growth restriction without pre-eclampsia was 13%, for pre-eclampsia irrespective of fetal growth restriction was 41% and for fetal growth restriction irrespective of pre-eclampsia was 16%. , so 69+ 24+16= 10 9% . The sensitivity of bilateral notches in predicting pre-eclampsia and/or fetal growth restriction was similar to that of increased pulsatility index but the screen-positive rate with notches (9.3%) was much higher than that with increased pulsatility index (5.1%).

 How do we define FGR??  Ans:-The sensitivity of fetal growth restriction defined by the 5th rather than the 10th centile was higher (19% vs. 16%). The sensitivity for both pre-eclampsia and fetal growth restriction was inversely related to the gestational age at delivery;
In early stage of gest the detection rate is high . When delivery occurred before 32 weeks, the sensitivity for all cases of pre-eclampsia with fetal growth restriction, pre-eclampsia without fetal growth restriction and fetal growth restriction without pre-eclampsia increased to 93%, 80% and 56%, respectively.



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