FGR
AND ROLE OF USG :-How relevant
is Doppler examination of the uterine arteries ? Out of 100 cases screened
for Ut A Doppler it is estimated that about 10% cases had early diastolic notches in the waveform
from both uterine arteries, Additionally in additional 11.1% cases there were notches unilaterally. Pre-eclampsia
with fetal growth restriction occurred in 0.5%
cases, pre-eclampsia without
fetal growth restriction in 0.9%
and fetal growth restriction
without pre-eclampsia in .9%.
The (sensitivity of increased
pulsatility index above the 95th centile,
Q. 2: What about umbilical artery?? At a mean gestational age
at 23 weeks Umb artery PI
(pulsatility index)--did not change significantly with gestation the median value of PI was 1.04 and the 95th centile was 1.63
If PI is 1.63 then we can conclude :--A) for
pre-eclampsia with fetal growth restriction was 69%, B) for
pre-eclampsia without fetal growth restriction was 24%, C) for fetal growth restriction without
pre-eclampsia was 13%, for pre-eclampsia irrespective of fetal growth restriction
was 41% and for fetal growth restriction irrespective of pre-eclampsia was 16%.
, so 69+ 24+16= 10 9% . The
sensitivity of bilateral notches in predicting pre-eclampsia and/or fetal
growth restriction was similar to that of increased pulsatility index but the
screen-positive rate with notches (9.3%) was much higher than that with
increased pulsatility index (5.1%).
How do
we define FGR?? Ans:-The sensitivity of fetal growth
restriction defined by the 5th rather than the 10th centile was higher (19% vs.
16%). The sensitivity for both
pre-eclampsia and fetal growth restriction was inversely related to the
gestational age at delivery;
In early stage of gest the
detection rate is high . When delivery occurred before 32 weeks, the
sensitivity for all cases of pre-eclampsia with fetal growth restriction,
pre-eclampsia without fetal growth restriction and fetal growth restriction
without pre-eclampsia increased to 93%, 80% and 56%, respectively.
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