Sunday, 6 October 2019

Zinc is an useful metal .It at optimum can allow body enzymes to act properly.


What we knew about Zinc and what we should know now about zinc? New information on Zinc:-Do you believe that Zinc is an essential micronutrient that plays an important role in many physiological functions , For instance Zinc act  as A)  cofactor in over  3000 proteins . B) It directly  regulates over 200 enzymes and hormones !!!! C) it controls growth   and cell renewal . Therefore its deficiency is associated with numerous diseases. It is important for growth and affects neuronal , muscular,  bone , skin  health and also controls immune functions. Therefore it is no surprise that   and its deficiency  increases the predisposition to infections . Physiological Action and pathophysiology
The pleiotropic and complex interactions of zinc affect multiple physiological functions and its deficiency can inhibit growth compromise the immune and nervous system and affect all other organ system
An optimum level of food & serum Zn improves pregnancy outcomes as well as bone skin and eye health of newborns.

How many members are aware that as many as A)  20% of the global population suffers from a zinc deficiency , One will be surprised to know that many such men & women are at   developing countries . AS a matter of fact those who exhibited low serum Zn in them as many as 61% of the population is at an increased risk of low dietary zinc intake . Zn in diet & blood is so relevant that few of the unexplained child mortality and disability may be due to Zn Deficincy alone .Its  deficiency in infants and children can affect growth and mental functions and cause  adolescent nutritional dwarfism.  
The untold story of a micronutrient??  How to combat presumed Zn deficiency & prevent TDM?? ? Universal Zn supplementation like universal iodine suppl in India?? Or else should we estimate serum Zn in all Indian population (population based screening in India) then consider Zn containing tablets. If that stands scientifically then too Q of finance comes in. Who will pay & how sensitive is the Zn  test !!!). It’s a mad mans thought. But the fact remains that in men & women with low serum Zn conc , if supplementation of   zinc is initiated as multivitamin containg high Zn then  such suppl can improve a number of diseases such as unexplained subfertility , respiratory infections, cardiovascular diseases , diabetes,  cancer and mental health disorders..
Epidemiology and risk factors
The recommended daily allowance of zinc is 15 mg for a male adult that can be achieved through diet. However it has been reported. In India an overall zinc deficiency of 43.8% was reported .. Deficiency rates of 49.4% in adolescent girls 52% in non pregnant woman and 64.6% in pregnant women have been observed.

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