Monday, 20 January 2020

Hyperandrogensim in peripubertal period decreses height of your daughter.


Phase 3 of growth spurt:- This, as far as I understand is the key issue in this post. This time growth tempo is 8- 14 35cm per yr.At this juncture growth hormone & sex steroids take upper hand than nutrition, candidate genes responsible for achieving target height. Calculation of target height is calculated by a simple formula father's height- 13 c m. + mother's height ÷ 2 . It is so easy.
Is there any standard table or say monogram for estimation of age specific standard height? Yes. The table is named after " Bayley- Pinneau Table for average girls which compares bone age ( as determined by left hand / wrist for correct estimation of bony age ) along with height exrpresed in inches.For details May see Net for details. One  is
is worried about therapeutic aspects of increasing the height. If no etiology is demonstrable ( Thyroid, anaemia, metabolic/ systemic diseases / endocrine disorders) - then Inj. Growth Hormone is recommended by U S .It is from 2003 .Such Inj. Is recommend for girls whe9 epipyses is not yet closed, and height is more than 2.25 standard deviations below the mean age for her age.But many endocrinologist are hesitant to prescribe such Inj. Arthur are of opinion that idiopathic short stature is no disease.How helpful is Inj. Growth Hormone ? After 5 years of treatment growth increase is only 5 years 4- 6 c m per yr.At c m in optimal cases but this who favour Inj. GH recommend that the treatment should initiate from 5 yrs to early puberty.


Childhood nutrition
And modification of puberty
Reproductive maturation is delayed in a nutritionally deprived environment. The effect of obesity on Pubertal timing has more recently been addressed in obese youth with premature pubarche in children with low birth weight and rapid postnatal catch-up in weight, and in boys and girls with simple obesity. These conditions will be addressed in coated reproductive disorders in adult.
The Effect of a Nutritionally Deprived Environment
Pugliese and colleagues evaluated 14 and girls. Nine boys and 5 girls, ages 9 to 17 years ,with growth failure and delay in puberty (7 of the 14)due to malnutrition resulting from self-imposed caloric restrictions. In these children,who restrictions caloric intake for fear of becoming obese increased linear growth and Pubertal progression resumed with the resumption of age-appropriate caloric intake. Matejek and colleagues studied the relationship between Leptin levels, fat stores , and reproductive hormone levels in 13 female juvenile elite gymnasts and 9 adolescent girl with anorexia nervosa . Leptin levels were subnormal and were related to body fat mass in girls with anorexia nervosa, but were lowest in the elite gymnasts. In both groups, estradiol levels were low and menarche was delayed. Catch-up height and weight In immigrant and adopted children, who move from developing to developed countries,is associated
with precocious menarche. Taken together, these studies support the notion that a critical body fat mass Is necessary for normal Pubertal progression.
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