Monday, 13 April 2020

Acute Pancreatitis -Etiology, Diag & treatment


Acute Pancreatitis in pregancy::--The attack is more common in third trimester and uncommon  in  first trimester. Prevalence of  Acute Pancreatitis in pregancy   is 1:10,000 preg women Heavy alcohol ingestion is the second possible cause, the third cause is hyper triglyceridaemia which should ideally be below 15 m.mol/L . Familial hypertriglyceridaemia is the most common cause of such high TG. . If excess serum TG (Familial) then supplement with omega 3 fatty acids which will reduce the synthesis of TG at liver. . Fibrates may be added too.

Diag: Symptoms are severe epigastric pain radiating to back, usually associated with N, Vomiting and later 10-20% may go to shock. May be confused with G B stone, peptic perfor Acute Pancreatitis in pregancy::--The attack is more common in third trimester and uncommon  in  first trimester. Prevalence of  Acute Pancreatitis in pregancy   is 1:10,000 preg women Heavy alcohol ingestion is the second possible cause, the third cause is hyper triglyceridaemia which should ideally be below 15 m.mol/L . Familial hypertriglyceridaemia is the most common cause of such high TG. . If excess serum TG (Familial) then supplement with omega 3 fatty acids which will reduce the synthesis of TG at liver. . Fibrates may be added too.

Diag: Symptoms are severe epigastric pain radiating to back, usually associated with N, Vomiting and later 10-20% may go to shock. May be confused with G B stone, peptic perforation. May be confused with heart attack, ARDS (Acute Resp Distress Syndrome).
  Investigations: USG to exclude GB stone. Diag: Serum amylase usually > 1000 U/L ; but mild elevation may be due to cholecystitis as well .

Treatement : To Admit allow ICU/ HDU facility  , Refer to surgeon, Whole abd USG ,.. Daily blood monitoring like  lipase , amylase ,Hb% TC DC, Creatinine, I/O chart, Na, K, O2  saturation LFT etc. Nasogastric suction, Liberal use of analgesics & Anticholinergics drugs.
ation. May be confused with heart attack, ARDS (Acute Resp Distress Syndrome).
  Investigations: USG to exclude GB stone. Diag: Serum amylase usually > 1000 U/L ; but mild elevation may be due to cholecystitis as well .

Treatement: To Admit allow ICU/ HDU facility  , Refer to surgeon, Whole abd USG ,.. Daily blood monitoring like  lipase , amylase ,Hb% TC DC, Creatinine, I/O chart, Na, K, O2  saturation LFT etc. Nasogastric suction, Liberal use of analgesics & Anticholinergics drugs.

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