, 16:-What is the most safe OCP – the
i.e. first choice COC for Early
reproductive Years in married women where the primary indication is
contraception :Ans:- Initial choice will be 20 , 25 ug EE OCs .
Admitting the fact that young women may
have increased bleeding problems on 20 ug OCPs
with a traditional 7 day pill free interval
or a 25 ug EE OCP but we should keep in mind that LNG
containg pills may result in better bleeding control in contrast to Cyproterone,
Desogestrel, Drospirenone , Gestodene (Femovan
brand) containg Pills.
LNG containg COC will have acceptable bleeding
control and will hopefully continue the pills after proper counseling. NSAID and or Tranexamic acid may be
supplemented if BTB occurs at all or she can consume two pills per days on the
days of BTB for two-three months provided1) BTB do not respond to Tx acid &
NSAID and 2) USG reveals no abnormality
in the form of polyps .In such an even she has to consume two packs for every 40-Days for two
months .Later she can switch over 21 days pack.
Reviews have shown levonorgestrel containing
OCs to have good bleeding
control .
Ideal COC in Late
reproductive Years?? Ans: The first choice menorrhagia is a problem: All OCPs
show will exhibit some benefit. Initially start with 20-25 ug EE OCs at this
age . But if
Menorrhagia is not well controlled
with low dosed OCP and it remains a
problem with first choice OCP then one should switch over to OCP with
levonorgestrel ( like Mala-D,N, Ecroz, Ovipauz-L, or Ovral-L one with lower EE
dose( 20 mcg is Femilon) . Switching to pill with higher progestin
to estrogen ratio results in less endometrial stimulation and may result in less menstrual bleeding .
Bleeding
problems all COCs will exhibit some
benefit if consumed properly and there is no organic pathology in uterus
or in system (hypothyroidism, ITP, HTN) . . If
midcycle bleeding and
spotting is a problem while on OC
consider switching to an CO with stronger progestin such as one with levonorgestrel or consider switching
to a higher EE dose OC Estrogen
increases endometrial growth and may improve
bleeding control In some
instances switching to a
lower EE done OC may be effective
because it lowers endometrial
stimulation which results in less endometrial tissue and less bleeding.
Right selection of COC in relatively elderly women: > 35 yrs :- We are aware that a perfectly healthy woman can safely continue the choiced COC upto the
age of 45 yers keeping a gap of 1 yers after 7 yrs of continued use(my
suggestion). .But problem arises in case
an a) relatively elderly woman including premenopausal woman is a smoker but
< 35 yrs or b) smokers less than 5 cigarettes per day > 35 yrs of
age c) or having mild Hypertension: if
any one of such coexistent abnormality is
associated the wisest choice will be
OCP with 20 mcg of EE( Loette, Femilon, Ovuloc, Intimacy plus 2, Yasmin,
Yaz, Crisanta-LS= all however contain Drospirenone except Loette) and not
high dose EE containg Pills and that
too for 2-3 yrs only.
. What about high dosed of OCP?? Because of
the higher potency of EE i.e. , OCPs
containing 30 / 35 ug EE age not ideal as first choice COC for such
relatively elderly women. However, given choice, I shall vouch strongly for
POPs.) minipills(oestrogen free pills)
or second generation POP Minikare -28 tab containg Lynesternol – 500 mcg
-) . There are other second generation
POP which are relatively safe for women with mild HTN, DM & CVS diseases
but unfortunately unavailable in India, Brand names are Micronor, Microoval,
Femiluen& neogest .Such POPO are excellent options for smokers, those who can’t
tolerate COC for nausea, mild DM obese
women and those who suffer from migraines as well.
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