Hyper-homocysteine is an intermediate formed during the breakdown of the amino acid methionine, and may 1) undergo remethylation to methionine, or 2) trans‐sulphuration to cystathione and cysteine.
Classic homocysteinaemia has been characterized as the accumulation of Hcy due to defects in Causes are two 1) enzymatic pathways. Recent research has pointed to many 2) second cause is :- non‐enzymatic factors which may influence Hcy levels—including age, gender, or sex‐steroid environment, nutrition, smoking, chronic inflammation and coffee consumption, and physical activity. Plasma Homocysteine, Fasting Insulin, and Androgen Patterns among Women with Polycystic Ovaries and Infertility
• homocysteine;
• polycystic ovary;
• hyperandrogenism;
• risk factors
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