Albinism:--It
is a genrtic disorder and the defective gene sharing is not uncommon in consanguineous marriages.
In consang.marriages defective gene which presumably passed down from both
parents to the child and ahs lead to albinism of the neonate. Different
gene defects characterize the numerous types of albinism. By contrast Vitiligo is more common than albinism.
Almost about 1 percent of
the world’s population has vitiligo. In this condition, the cells that are
responsible for skin color are
destroyed. Melanocytes cells, , no longer produce skin pigment, called melanin.
So, areas of skin will lose color or turn white. Areas of lost pigment can develop anywhere in body,
including: sun-exposed areas like the
hands, feet, arms, and face inside the
mouth or other mucus membranes, nostrils, genitals, back of the
eye,
within
the hearing system of the ears. t’s unknown exactly what causes vitiligo. The
condition doesn’t appear to be inherited. Most people with vitiligo don’t have
a family
history of the disorder. But family history of vitiligo or
other autoimmune conditions may increase your risk even though it doesn’t cause
vitiligo.Another
risk factor may be having genes associated with vitiligo, including NLRP1 and
PTPN22
Most researchers believe that vitiligo is an autoimmune
disorder because your body is attacking your own cells. But it’s also unclear
how your body attacks your pigment cells. What is known is that about 20
percentTrusted Source of people with
vitiligo also have one other autoimmune disorder. Depending on the population,
these disorders can include the following, from most common to least common:
scleroderma, a disorder of the connective tissue of the body
lupus
thyroiditis, caused by an improperly functioning thyroid
psoriasis
alopecia areata, or baldness
type 1 diabetes
pernicious anemia, an inability to absorb vitamin B-12
Addison’s disease
rheumatoid arthritis
Some experts also report vitiligo appearing after incidents
of:
severe sunburns or cuts
exposure to toxins and chemicals
high levels of stress
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