Monday, 23 September 2019

Indication of ICSI (intra cytoplasm sperm injection) in male factor subfrtility an advanced method of I V F.

What are the indications when a couple is advised to undergo ICSI(Intra cytoplasmic sperm injection into the  egg cells through a spl needle piercing  Zona & oolemma?  What do we mean by the process of sperm / Round sperm (immature) retrieval from epididymis/ testis? What does the abbreviation means too us??
 testis 1) PESA 2) MESA, 3) TESA & 4) Micro  TESE ??
Part A) What is the evolution or History of ICSI? One junior doctor was asked to push the sperm in subzonal space due to hard zona,. But he that in ICSI the head only is injected ). Surprisingly the research team at Brussels ( where Flower show is famous and I had the opportunity to be resent twice in that particular season) the oocyte accidentally pushed the head of sperm (we know got fertilized,. This encouraged the researchers of Brussels to abandon the method of injecting sperm in subzonal space but directly at cytoplasm of mature oocyte, That is the reason the procedure is globally termed as cytoplasmic transfer and not subzonal transfer. :-Initially used for used to overcome the barrier of zona pellucida because it is possible that the zona becomes hard for sperm penetration due to its prolonged exposure to culture media

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