Sunday, 10 November 2019

Does magnesium potentiates the action of endogenous insulin?? •


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·         PCO women with high PPBS, HbA1C or documented   IR?? Many women with PCOS have significantly low serum and total magnesium, contributing to the progression of insulin resistance to type 2 diabetes and heart disease. Magnesium insufficiency is common in poorly controlled type 2 diabetes patients. In one study, 128 patients with poorly controlled type 2 diabetes received a placebo or a supplement with either 500 mg or 1000 mg of magnesium oxide (300 mg or 600 mg element magnesium) for 30 days. All patients were treated also with diet or diet plus oral medication to control blood glucose levels. Magnesium levels increased in the group receiving 1,000 mg magnesium oxide daily but did not significantly change in the placebo group or the group receiving 500 mg of magnesium. The author suggested prolonged use of magnesium in doses that are higher than usual is needed in patients with type 2 diabetes to improve control or prevent chronic complications .
In a related study, 63 diabetics with below normal serum magnesium levels received either 2.5 grams of oral magnesium chloride daily or a placebo. At the end of the 16-week study period, those who received the supplement had higher blood levels of magnesium and improved control of diabetes, as suggested by lower hemoglobin A1c (HbA1c) levels.
Point 1 Mg SO4 :-Another study found that oral magnesium supplements helped insulin resistant individuals avoid developing type 2 diabetes.
Since magnesium improves insulin-mediated glucose uptake and insulin secretion in type 2 diabetes patients, it is considered a critical mineral for women with PCOS.
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·         https://static.xx.fbcdn.net/rsrc.php/v3/yA/r/6zTRlzzrMzf.png?_nc_x=30soTrIyvMi&_nc_eui2=AeHkD8T_6ZDOMxuqqNlFSvJ8y4PVPFeBlQmP96nkx-0uNKPaarxV8CWnMmYiWi4mE9OlG7cZbFbj0x3uCps7ywm3ICCgkQIKet_yzy7Fbk-2Lg B) In PIH:-: May read an useful article " Examining the Use of Magnesium Sulfate to Treat Pregnant Women with Preeclampsia and Eclampsia: Results of a Program Assessment of Emergency Obstetric Care (EmOC) Training in India"-
Henna Budhwani1 • Poonam Shivkumar2 • Chittaranjan Narhari Purandare2 • Nicholas A. Cataldo1 • Sadhana Desai4 • Prakash Bhatt4 • Dinesh Baswal5 • Ajey Bhardwaj
Received: 4 October 2016/Accepted: 11 January 2017/Published online: 10 February 2017 © Federation of Obstetric & Gynecological Societies of India 2017
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