Thursday, 21 November 2019

Menopuse a topic littlke discussed: The subject of the World Health Day in the year 2017 was “Let’s talk: Depression.”: Then why not menopause??



The subject of the World Health Day in the year 2017  was “Let’s talk: Depression.”: Then why not menopause?? Members pl proceed for one day strike. However, Let’s see your skill on counseling to a menopausal women on following issues: How do you counsel & what advise U offer to a housewife, Executive, Political women-all at menopausal group. What your message to meno women as an imp person of the society at  large?? Treating physician experience on managing meno safely & comfort level (TREAT THE PATIENT &  Menopause (HRT or no HRT –decision is yours). Many Exciting developments in the recent past on Cardiac & bone health. Lets discuss in a truly Socratic manner . Discuss , debate on new developments on cardiac, endometrial, Breast and above all on musculo skeletal health  & finally analyze what we mean by
Menopausal: a) hypoactive sexual desire disorder (HSDD) b) Female sexual dysfunction (FSD)  c)
Menopause & depression d) Mood disorder e) Neuropsychological co-morbidities .f) Peri –menopausal mood disorders premenstrual syndrome g) Hot flashes nocturnal sweating and insomnia


Having admitted that the common symptoms of Menopause:-are 1) Vasomotor symptoms
2) Hot flushes night sweats and palpitations ( non hormonal therapy if memberers so desires to prescribe is Arkamin) 3) The third symp is
Sleep fragmentation resulting in day time fatigue
4) Symptoms of fibromyalgia dand lastly 5)
Behavioral interventions & urinary symp and vaginal dryness, (mentioned above). Problems are known,. OK . Now what are the options we have before us? What to proscribe? Here are some tips on treating a meno symp & Asymp woman.


Tibolone is a synthetic steroid commonly used for the treatment of climacteric complaints and prevention of osteoporosis in postmenopausal       women. The human endometrium synthesizes estrogen via a number of enzymes Sulphatase  which converts inactive estrone sulfate to estrone aromatase and 17 hydroxysteroid dehydrogenase type 1 activity both of which stimulate the metabolism of androgens androstenedione and testosterone to estradiol . Preogestogens downregulates  the estrogen forming enzymes and also induce estrogen inactivating enzymes such as 17 HSD type 2.The consequence of these enzymatic activities is the endometrial conversion of estradiol to the less bioactive estrogen estrone such synthesis of estrogen continues in all women in menopausal period but to varying degrees in estrogen sensitive issues such as the endometrium.

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