The subject of the World Health Day
in the year 2017 was “Let’s talk: Depression.”:
Then why not menopause?? Members pl proceed for one day strike. However, Let’s see your skill on counseling to a menopausal
women on following issues: How do you counsel & what advise U offer to a
housewife, Executive, Political women-all at menopausal group. What your
message to meno women as an imp person of the society at large?? Treating physician experience on
managing meno safely & comfort level (TREAT THE PATIENT & Menopause (HRT
or no HRT –decision is yours). Many Exciting developments in the recent
past on Cardiac & bone health. Lets discuss in a truly Socratic manner . Discuss , debate on
new developments on cardiac, endometrial, Breast and above all on musculo
skeletal health & finally analyze
what we mean by
Menopausal:
a) hypoactive sexual desire disorder (HSDD) b) Female sexual dysfunction
(FSD) c)
Menopause
& depression d) Mood disorder e) Neuropsychological co-morbidities .f) Peri
–menopausal mood disorders premenstrual syndrome g) Hot flashes nocturnal
sweating and insomnia
Having admitted that the common symptoms of Menopause:-are 1) Vasomotor symptoms
2) Hot flushes night
sweats and palpitations ( non hormonal therapy if memberers so desires to
prescribe is Arkamin) 3) The third symp is
Sleep fragmentation
resulting in day time fatigue
4) Symptoms of fibromyalgia
dand lastly 5)
Behavioral interventions
& urinary symp and vaginal dryness, (mentioned above). Problems are known,.
OK . Now what are the options we have before us? What to proscribe? Here are some
tips on treating a meno symp & Asymp woman.
Tibolone is a synthetic steroid commonly used
for the treatment of climacteric complaints and prevention of osteoporosis in
postmenopausal women. The human
endometrium synthesizes estrogen via a number of enzymes Sulphatase which converts inactive estrone sulfate to
estrone aromatase and 17 hydroxysteroid dehydrogenase type 1 activity both of
which stimulate the metabolism of androgens androstenedione and testosterone to
estradiol . Preogestogens downregulates the estrogen forming enzymes and also induce
estrogen inactivating enzymes such as 17 HSD type 2.The consequence of these
enzymatic activities is the endometrial conversion of estradiol to the less
bioactive estrogen estrone such synthesis of estrogen continues in all women in
menopausal period but to varying degrees in estrogen sensitive issues such as
the endometrium.
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