Role of Antioxidants and vitamins in male
subfertility:-Many doctors do prescribe 1)L- carnitine,2) Astaxanthin,3) Vitamin E, 4) Vitamin C, 5) Co-Q, 6) Zn, 7) Lycopene, 8) Selenium, 9)
L-arginine, 10) Alpha- Calcidol, 11) Omega-3 Fatty acids, 12) DHA and 13) F.
Acid 14) Glutathione to promote
fertilizing potential of ejaculated sperms.. It is understandable that role of antioxidants in male subfertility is
somewhat effective
as time and again it has been noticed
that the quantum of ROS in seminal fluid
is high when seminal parameters are substandard. ?? There is no head to head trial with IUI as initial modality for suboptimal seminal parameters vis
a vis antioxidants as first modality?? I
have no idea but literature is full of positive role of antioxidants in male subfertility. AS such ,
still many people use varieties of antioxidants in male partner defect in
empirical basis with some improvement in selected cases but not in all.
What Antioxidants to improve seminal
parameters and conception rate!!! Do
supplementary oral antioxidants improve fertility outcomes for subfertile men
when compared with placebo, no treatment or another? Recognizing the drugs are
safe in prescribed dosage but not all the mentioned agents are available in any
brand prepaertions.
Cost is an issue:-Antioxidants prescribed at
right dose as male partner defect to counteract ROS in semen will cost approx > Rs
110-150/- per day and given the earliest possible pregancy will be 80-90 days
as spermatogenic cycle is somewhere 74 days. Given this equation, which one is
cost effective??. If one intends to improve one or multiple parameter defect
when no clinical abnormality is demonstrable then antioxidants is one modality
of improving seminal parameters. What antioxidants to improve seminal
parameters and conception rate!!!.
Do supplementary oral antioxidants improve take
home baby rate fertility outcomes for subfertile men when compared with
placebo, no treatment or another?
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