Should boys be also vaccinated against Genital HPV?? Ans: Eight studies so far reported that vaccinating adolescent boys in addition to girls was cost-effective. However, two studies further specified that this vaccination strategy was no longer cost-effective when vaccine coverage for female is above 75%. Majority of the cost-effective studies comprehensively captured all HPV-related diseases including male-associated cancers such as penile and oropharyngeal cancer. Hence, the assumption of lower female vaccine coverage and the inclusion of male-associated HPV diseases would result in a more favourable conclusion for the gender-neutral HPV vaccination strategy.
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